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Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ER...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoyu, Yang, Haisheng, Bullock, Whitney A., Gallant, Maxim A., Ohlsson, Claes, Bellido, Teresita M., Main, Russell P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108310/
https://www.ncbi.nlm.nih.gov/pubmed/36321245
http://dx.doi.org/10.1002/jbmr.4731