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Modulation of ERK5 Activity as a Therapeutic Anti-Cancer Strategy

[Image: see text] The extracellular signal-regulated kinase 5 (ERK5) signaling pathway is one of four conventional mitogen-activated protein (MAP) kinase pathways. Genetic perturbation of ERK5 has suggested that modulation of ERK5 activity may have therapeutic potential in cancer chemotherapy. This...

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Detalles Bibliográficos
Autores principales: Miller, Duncan C., Harnor, Suzannah J., Martin, Mathew P., Noble, Richard A., Wedge, Stephen R., Cano, Celine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108346/
https://www.ncbi.nlm.nih.gov/pubmed/37002872
http://dx.doi.org/10.1021/acs.jmedchem.3c00072