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Serine-/Cysteine-Based sp(2)-Iminoglycolipids as Novel TLR4 Agonists: Evaluation of Their Adjuvancy and Immunotherapeutic Properties in a Murine Model of Asthma

[Image: see text] Glycolipids with TLR4 agonistic properties can serve either as therapeutic agents or as vaccine adjuvants by stimulating the development of proinflammatory responses. Translating them to the clinical setting is hampered by synthetic difficulties, the lack of stability in biological...

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Detalles Bibliográficos
Autores principales: González-Cuesta, Manuel, Lai, Alan Chuan-Ying, Chi, Po-Yu, Hsu, I-Ling, Liu, Nien-Tzu, Wu, Ko-Chien, García Fernández, José M., Chang, Ya-Jen, Ortiz Mellet, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108363/
https://www.ncbi.nlm.nih.gov/pubmed/36958376
http://dx.doi.org/10.1021/acs.jmedchem.2c01948