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Serine-/Cysteine-Based sp(2)-Iminoglycolipids as Novel TLR4 Agonists: Evaluation of Their Adjuvancy and Immunotherapeutic Properties in a Murine Model of Asthma
[Image: see text] Glycolipids with TLR4 agonistic properties can serve either as therapeutic agents or as vaccine adjuvants by stimulating the development of proinflammatory responses. Translating them to the clinical setting is hampered by synthetic difficulties, the lack of stability in biological...
Autores principales: | González-Cuesta, Manuel, Lai, Alan Chuan-Ying, Chi, Po-Yu, Hsu, I-Ling, Liu, Nien-Tzu, Wu, Ko-Chien, García Fernández, José M., Chang, Ya-Jen, Ortiz Mellet, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108363/ https://www.ncbi.nlm.nih.gov/pubmed/36958376 http://dx.doi.org/10.1021/acs.jmedchem.2c01948 |
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