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Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury

BACKGROUND: Human mesenchymal stromal cell (MSC)-derived extracellular vesicles (EV) revealed neuroprotective potentials in various brain injury models, including neonatal encephalopathy caused by hypoxia–ischemia (HI). However, for clinical translation of an MSC-EV therapy, scaled manufacturing str...

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Detalles Bibliográficos
Autores principales: Labusek, Nicole, Mouloud, Yanis, Köster, Christian, Diesterbeck, Eva, Tertel, Tobias, Wiek, Constanze, Hanenberg, Helmut, Horn, Peter A., Felderhoff-Müser, Ursula, Bendix, Ivo, Giebel, Bernd, Herz, Josephine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108458/
https://www.ncbi.nlm.nih.gov/pubmed/37069694
http://dx.doi.org/10.1186/s41232-023-00274-6