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Using RNA-seq to identify suitable housekeeping genes for hypoxia studies in human adipose-derived stem cells
BACKGROUND: Hypoxic culture conditions have been used to study the impact of oxygen deprivation has on gene expression in a number of disease models. However, hypoxia response elements present in the promoter regions of some commonly used housekeeping genes, such as GAPDH and PGK1, can confound the...
Autores principales: | Ong, Huan Ting, Prêle, Cecilia M., Dilley, Rodney J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108514/ https://www.ncbi.nlm.nih.gov/pubmed/37062833 http://dx.doi.org/10.1186/s12860-023-00475-4 |
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