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Adoptive neoantigen-reactive T cell therapy: improvement strategies and current clinical researches

Neoantigens generated by non-synonymous mutations of tumor genes can induce activation of neoantigen-reactive T (NRT) cells which have the ability to resist the growth of tumors expressing specific neoantigens. Immunotherapy based on NRT cells has made preeminent achievements in melanoma and other s...

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Detalles Bibliográficos
Autores principales: Huang, Ruichen, Zhao, Bi, Hu, Shi, Zhang, Qian, Su, Xiaoping, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108522/
https://www.ncbi.nlm.nih.gov/pubmed/37062844
http://dx.doi.org/10.1186/s40364-023-00478-5