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Adoptive neoantigen-reactive T cell therapy: improvement strategies and current clinical researches
Neoantigens generated by non-synonymous mutations of tumor genes can induce activation of neoantigen-reactive T (NRT) cells which have the ability to resist the growth of tumors expressing specific neoantigens. Immunotherapy based on NRT cells has made preeminent achievements in melanoma and other s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108522/ https://www.ncbi.nlm.nih.gov/pubmed/37062844 http://dx.doi.org/10.1186/s40364-023-00478-5 |