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Chromatin accessibility differences between alpha, beta, and delta cells identifies common and cell type-specific enhancers

BACKGROUND: High throughput sequencing has enabled the interrogation of the transcriptomic landscape of glucagon-secreting alpha cells, insulin-secreting beta cells, and somatostatin-secreting delta cells. These approaches have furthered our understanding of expression patterns that define healthy o...

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Detalles Bibliográficos
Autores principales: Mawla, Alex M., van der Meulen, Talitha, Huising, Mark O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108528/
https://www.ncbi.nlm.nih.gov/pubmed/37069576
http://dx.doi.org/10.1186/s12864-023-09293-6