Cargando…

Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling

Triple-negative breast cancer (TNBC) exhibits the poorest outcomes among breast cancer subtypes due to the high heterogeneity and a lasting scarcity of effectual treatments. Targeted therapies based on molecular subtypes of TNBC are critical step toward tailoring treatments to improve clinical outco...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Heshu, Yan, Rui, Xiao, Zeru, Huang, Xuying, Yao, Jiannan, Liu, Jian, An, Guangyu, Ge, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108533/
https://www.ncbi.nlm.nih.gov/pubmed/37069669
http://dx.doi.org/10.1186/s13058-023-01642-3