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NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss
BACKGROUND: Inflammaging represents an accepted concept where the immune system shifts to a low-grade chronic pro-inflammatory state without overt infection upon aging. In the CNS, inflammaging is mainly driven by glia cells and associated with neurodegenerative processes. White matter degeneration...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108549/ https://www.ncbi.nlm.nih.gov/pubmed/37069623 http://dx.doi.org/10.1186/s13024-023-00616-5 |