NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss

BACKGROUND: Inflammaging represents an accepted concept where the immune system shifts to a low-grade chronic pro-inflammatory state without overt infection upon aging. In the CNS, inflammaging is mainly driven by glia cells and associated with neurodegenerative processes. White matter degeneration...

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Detalles Bibliográficos
Autores principales: Schlett, Judith Stefanie, Mettang, Melanie, Skaf, Aladdin, Schweizer, Pavel, Errerd, Alina, Mulugeta, Ephraim Alemayehu, Hein, Tabea Melissa, Tsesmelis, Konstantinos, Tsesmelis, Miltiadis, Büttner, Ulrike F. G., Wendt, Heinrich, Abaei, Alireza, Rasche, Volker, Prex, Vivien, Nespoli, Ester, Alami, Najwa Ouali, Tews, Daniel, Walther, Paul, Yilmazer-Hanke, Deniz, Oswald, Franz, Dimou, Leda, Wirth, Thomas, Baumann, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108549/
https://www.ncbi.nlm.nih.gov/pubmed/37069623
http://dx.doi.org/10.1186/s13024-023-00616-5

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