Beyond antibody fucosylation: α-(1,6)-fucosyltransferase (Fut8) as a potential new therapeutic target for cancer immunotherapy

Aberrant post-translational glycosylation is a well-established hallmark of cancer. Altered core fucosylation mediated by α-(1,6)-fucosyltransferase (Fut8) is one of the key changes in tumor glycan patterns that contributes to neoplastic transformation, tumor metastasis, and immune evasion. Increase...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Changchuin, Li, Jun, Feng, Lili, Gao, Wenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108557/
https://www.ncbi.nlm.nih.gov/pubmed/37077473
http://dx.doi.org/10.1093/abt/tbad004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108557/
https://www.ncbi.nlm.nih.gov/pubmed/37077473
http://dx.doi.org/10.1093/abt/tbad004

Ejemplares similares