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Beyond antibody fucosylation: α-(1,6)-fucosyltransferase (Fut8) as a potential new therapeutic target for cancer immunotherapy

Aberrant post-translational glycosylation is a well-established hallmark of cancer. Altered core fucosylation mediated by α-(1,6)-fucosyltransferase (Fut8) is one of the key changes in tumor glycan patterns that contributes to neoplastic transformation, tumor metastasis, and immune evasion. Increase...

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Detalles Bibliográficos
Autores principales:	Mao, Changchuin, Li, Jun, Feng, Lili, Gao, Wenda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108557/ https://www.ncbi.nlm.nih.gov/pubmed/37077473 http://dx.doi.org/10.1093/abt/tbad004

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