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Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden

Keloids are skin tumours caused by aberrant growth of dermal fibroblasts. Cellular senescence contributes to aging and various pathological conditions, including cancer, atherosclerosis, and fibrotic diseases. However, the effects of cellular senescence and senolytic drugs on keloids remain largely...

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Detalles Bibliográficos
Autores principales: DARMAWAN, Claudia C., HUR, Keunyoung, KUSUMANINGRUM, Novi, CHUNG, Jin Ho, LEE, Si-Hyung, MUN, Je-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Journals Sweden, on behalf of the Society for Publication of Acta Dermato-Venereologica 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108619/
https://www.ncbi.nlm.nih.gov/pubmed/37021598
http://dx.doi.org/10.2340/actadv.v103.4475