Cargando…

Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden

Keloids are skin tumours caused by aberrant growth of dermal fibroblasts. Cellular senescence contributes to aging and various pathological conditions, including cancer, atherosclerosis, and fibrotic diseases. However, the effects of cellular senescence and senolytic drugs on keloids remain largely...

Descripción completa

Detalles Bibliográficos
Autores principales:	DARMAWAN, Claudia C., HUR, Keunyoung, KUSUMANINGRUM, Novi, CHUNG, Jin Ho, LEE, Si-Hyung, MUN, Je-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medical Journals Sweden, on behalf of the Society for Publication of Acta Dermato-Venereologica 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108619/ https://www.ncbi.nlm.nih.gov/pubmed/37021598 http://dx.doi.org/10.2340/actadv.v103.4475

Ejemplares similares

Adiponectin-Based Peptide (ADP355) Inhibits Transforming Growth Factor-β1-Induced Fibrosis in Keloids
por: Darmawan, Claudia C., et al.
Publicado: (2020)

Quality evaluation of YouTube videos as a source of information on warts
por: Ha, Eun Seo, et al.
Publicado: (2022)

Pachyonychia Congenita with a Novel Variant in the KRT16 Gene, c.348_379delinsAA
por: Hur, Keunyoung, et al.
Publicado: (2022)

Secondary Intention Healing After Functional Surgery for In situ or Minimally Invasive Nail Melanoma
por: JO, Gwanghyun, et al.
Publicado: (2020)

Dasatinib Plus Quercetin Alleviates Choroid Neovascularization by Reducing the Cellular Senescence Burden in the RPE–Choroid
por: Wang, Yinhao, et al.
Publicado: (2023)

Acral lentiginous melanoma in situ: dermoscopic features and management strategy
por: Han, Byeol, et al.
Publicado: (2020)

Is the Mitochondrial Function of Keloid Fibroblasts Affected by Cytoglobin?
por: Jusman, Sri Widia A, et al.
Publicado: (2021)

Dermoscopic Evaluation of Inflammatory Nail Disorders and Their Mimics
por: LIM, Sophie Soyeon, et al.
Publicado: (2021)

Effect of Combined Dasatinib and Fisetin Treatment on Senescent Cell Clearance in Monkeys
por: Colman, Ricki, et al.
Publicado: (2020)

Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model
por: Balasubramanian, Sundaravadivel, et al.
Publicado: (2015)

Isorhamnetin attenuates the proliferation, invasion, migration and fibrosis of keloid fibroblasts by targeting S1PR1
por: Pu, Xiaoshu, et al.
Publicado: (2023)

Hydroxychloroquine-associated pigmentation after extravasation injury
por: Hur, Keunyoung, et al.
Publicado: (2021)

Tauroursodeoxycholic Acid Decreases Keloid Formation by Reducing Endoplasmic Reticulum Stress as Implicated in the Pathogenesis of Keloid
por: Kim, Sunje, et al.
Publicado: (2021)

Reduction in Lens Epithelial Cell Senescence Burden through Dasatinib Plus Quercetin or Rapamycin Alleviates D-Galactose-Induced Cataract Progression
por: Wang, Yinhao, et al.
Publicado: (2022)

Hydroa vacciniforme-like lymphoproliferative disorder in Korea
por: Han, Byeol, et al.
Publicado: (2020)

Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis
por: Cruz, Fernanda Ferreira, et al.
Publicado: (2016)

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
por: Hickson, LaTonya J., et al.
Publicado: (2019)

Biomechanical Regulatory Factors and Therapeutic Targets in Keloid Fibrosis
por: Feng, Fan, et al.
Publicado: (2022)

Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids
por: Lee, Won Jai, et al.
Publicado: (2017)

A Dasatinib-Induced Chylothorax Persisting After the Discontinuation of Dasatinib
por: Bradt, Nicolas, et al.
Publicado: (2022)

Rare experience of keloidal dermatofibroma of forehead
por: Kim, Ji Min, et al.
Publicado: (2018)

Keloids
por: Brown, William Augustus
Publicado: (1873)

Clinical and genetic profiling of nevoid basal cell carcinoma syndrome in Korean patients by whole-exome sequencing
por: Kim, Boram, et al.
Publicado: (2021)

Adjuvant Radiotherapy after Surgical Excision in Keloids
por: Lee, Jeong Won, et al.
Publicado: (2021)

Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice
por: Cavalcante, Marcelo B., et al.
Publicado: (2020)

Dasatinib plus quercetin attenuates some frailty characteristics in SAMP10 mice
por: Ota, Hidetaka, et al.
Publicado: (2022)

High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis
por: Maique, Jenny, et al.
Publicado: (2020)

Keloids in Scleroderma-Keloidal Scleroderma: A Unique Entity
por: Sen, Sumit, et al.
Publicado: (2013)

Dasatinib-Related Chylothorax
por: Huang, Yen-Min, et al.
Publicado: (2015)

DASATINIB-RELATED CHYLOTHORAX
por: Young, Katherine, et al.
Publicado: (2019)

Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts
por: Shin, Jung U, et al.
Publicado: (2015)

Predictive Factors of Keloid Formation in Congenital Foot Syndactyly
por: Oh, Sang Ho, et al.
Publicado: (2021)

Mycobacteria in keloid
por: Singh, Ashish, et al.
Publicado: (2011)

Keloid Growths
Publicado: (1899)

Incisional keloid
por: Sakthivel, Pirabu, et al.
Publicado: (2018)

Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer
por: Kovacovicova, Kristina, et al.
Publicado: (2018)

Senescence-Independent Anti-Inflammatory Activity of the Senolytic Drugs Dasatinib, Navitoclax, and Venetoclax in Zebrafish Models of Chronic Inflammation
por: Hernández-Silva, David, et al.
Publicado: (2022)

Rupatadine Protects against Pulmonary Fibrosis by Attenuating PAF-Mediated Senescence in Rodents
por: Lv, Xiao-xi, et al.
Publicado: (2013)

Risk factors associated with the progression from keloids to severe keloids
por: Liu, Ruolin, et al.
Publicado: (2022)

The Detroit Keloid Scale: A Validated Tool for Rating Keloids
por: Lyons, Alexis B., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8n8ce509b2a6qq7d6a1rbheca3