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Mesenchymal Stromal Cells Suppress T-Cell-Mediated Delayed-Type Hypersensitivity via ALCAM-CD6 Interaction

Mounting evidence suggests mesenchymal stromal cells (MSCs) suppress CD4(+) T-cell activation, but whether MSCs directly regulate activation and expansion of allogeneic T cells has not been fully deciphered. Here, we identified that both human and murine MSCs constitutively express ALCAM, a cognate...

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Detalles Bibliográficos
Autores principales: Cho, WonKyung J, Mittal, Sharad K, Chauhan, Sunil K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108723/
https://www.ncbi.nlm.nih.gov/pubmed/36972356
http://dx.doi.org/10.1093/stcltm/szad012