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P066 A randomised, double-blind, placebo-controlled, single-dose, crossover, pilot study investigating the effects of cannabinol (CBN) 30 mg and 300 mg on sleep architecture and next-day function in insomnia disorder

INTRODUCTION: There is a clear need for novel interventions for insomnia disorder. Growing evidence suggests a role of the endogenous cannabinoid system in regulating circadian sleep-wake cycles, highlighting a potential avenue for novel therapeutics. Cannabinol (CBN), a trace cannabinoid formed thr...

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Detalles Bibliográficos
Autores principales: Lavender, I, Suraev, A, McCartney, D, Irwin, C, Kevin, R, D'Rozario, A, Gordon, C, Marshall, N, Saini, B, McGregor, I, Grunstein, R, Yee, B, Hoyos, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109170/
http://dx.doi.org/10.1093/sleepadvances/zpac029.137