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RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion

Cancer stem cells (CSC) within non–small cell lung carcinoma (NSCLC) tumors drive NSCLC progression, metastasis, relapse, and intrinsic chemoresistance. Understanding the mechanisms that support the malignant phenotypes of NSCLC CSCs may provide insights for improved NSCLC therapeutic interventions....

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Detalles Bibliográficos
Autores principales: Meneses, Kayleah M., Pandya, Prita, Lindemann, Jennifer A., Al-Qasrawi, Dania S., Argo, Ryan A., Weems, Celeste M., Beetler, Danielle J., Vijay, Geraldine V., Yan, Irene K., Wolfram, Joy, Patel, Tushar, Justilien, Verline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109210/
https://www.ncbi.nlm.nih.gov/pubmed/37077938
http://dx.doi.org/10.1158/2767-9764.CRC-22-0425