Drug-target interaction prediction based on spatial consistency constraint and graph convolutional autoencoder

BACKGROUND: Drug-target interaction (DTI) prediction plays an important role in drug discovery and repositioning. However, most of the computational methods used for identifying relevant DTIs do not consider the invariance of the nearest neighbour relationships between drugs or targets. In other wor...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Peng, Zheng, Haoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109239/
https://www.ncbi.nlm.nih.gov/pubmed/37069493
http://dx.doi.org/10.1186/s12859-023-05275-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109239/
https://www.ncbi.nlm.nih.gov/pubmed/37069493
http://dx.doi.org/10.1186/s12859-023-05275-3

Ejemplares similares