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PRNP expression predicts imaging findings in sporadic Creutzfeldt‐Jakob disease

OBJECTIVE: We explored the relationship between regional PRNP expression from healthy brain tissue and patterns of increased and decreased diffusion and regional brain atrophy in patients with sporadic Creutzfeldt‐Jakob disease (sCJD). METHODS: We used PRNP microarray data from 6 healthy adult brain...

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Detalles Bibliográficos
Autores principales: Broce, Iris J., Caverzasi, Eduardo, Sacco, Simone, Nillo, Ryan Michael, Paoletti, Matteo, Desikan, Rahul S., Geschwind, Michael, Sugrue, Leo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109249/
https://www.ncbi.nlm.nih.gov/pubmed/36744645
http://dx.doi.org/10.1002/acn3.51739