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Th2-dependent STAT6-regulated genes in intestinal epithelial cells mediate larval trapping during secondary Heligmosomoides polygyrus bakeri infection

Gastrointestinal helminths are a major health threat worldwide. Alternatively activated macrophages (AAMs) have been shown to contribute to host protection during secondary helminth infections. AAMs express effector molecules that depend on activation of the IL-4- or IL-13-induced transcription fact...

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Detalles Bibliográficos
Autores principales: Westermann, Stefanie, Schubart, Christoph, Dietschmann, Axel, Castiglione, Kirstin, Radtke, Daniel, Voehringer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109486/
https://www.ncbi.nlm.nih.gov/pubmed/37018382
http://dx.doi.org/10.1371/journal.ppat.1011296