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Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage

To prevent chromosome mis-segregation, a surveillance mechanism known as the spindle checkpoint delays the cell cycle if kinetochores are not attached to spindle microtubules, allowing the cell additional time to correct improper attachments. During spindle checkpoint activation, checkpoint proteins...

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Detalles Bibliográficos
Autores principales: MacKenzie, Anne, Vicory, Victoria, Lacefield, Soni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109492/
https://www.ncbi.nlm.nih.gov/pubmed/37018287
http://dx.doi.org/10.1371/journal.pgen.1010707