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Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage
To prevent chromosome mis-segregation, a surveillance mechanism known as the spindle checkpoint delays the cell cycle if kinetochores are not attached to spindle microtubules, allowing the cell additional time to correct improper attachments. During spindle checkpoint activation, checkpoint proteins...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109492/ https://www.ncbi.nlm.nih.gov/pubmed/37018287 http://dx.doi.org/10.1371/journal.pgen.1010707 |