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Dual contribution of ASIC1a channels in the spinal processing of pain information by deep projection neurons revealed by computational modeling
Dorsal horn of the spinal cord is an important crossroad of pain neuraxis, especially for the neuronal plasticity mechanisms that can lead to chronic pain states. Windup is a well-known spinal pain facilitation process initially described several decades ago, but its exact mechanism is still not ful...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10109503/ https://www.ncbi.nlm.nih.gov/pubmed/37068087 http://dx.doi.org/10.1371/journal.pcbi.1010993 |