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Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in Drosophila

Modification by sialylated glycans can affect protein functions, underlying mechanisms that control animal development and physiology. Sialylation relies on a dedicated pathway involving evolutionarily conserved enzymes, including CMP-sialic acid synthetase (CSAS) and sialyltransferase (SiaT) that m...

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Detalles Bibliográficos
Autores principales: Scott, Hilary, Novikov, Boris, Ugur, Berrak, Allen, Brooke, Mertsalov, Ilya, Monagas-Valentin, Pedro, Koff, Melissa, Baas Robinson, Sarah, Aoki, Kazuhiro, Veizaj, Raisa, Lefeber, Dirk J, Tiemeyer, Michael, Bellen, Hugo, Panin, Vladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110239/
https://www.ncbi.nlm.nih.gov/pubmed/36946697
http://dx.doi.org/10.7554/eLife.78280