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Omicsynin B4 potently blocks coronavirus infection by inhibiting host proteases cathepsin L and TMPRSS2
The emergence of SARS-CoV-2 variants represents a major threat to public health and requires identification of novel therapeutic agents to address the unmet medical needs. Small molecules impeding viral entry through inhibition of spike protein priming proteases could have potent antiviral effects a...
Autores principales: | Li, Yihua, Wang, Kun, Sun, Hongmin, Wu, Shuo, Wang, Huiqiang, Shi, Yuanyuan, Li, Xingxing, Yan, Haiyan, Yang, Ge, Wu, Mengyuan, Li, Yihong, Ding, Xiaotian, Si, Shuyi, Jiang, Jiandong, Du, Yu, Li, Yuhuan, Hong, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110284/ https://www.ncbi.nlm.nih.gov/pubmed/37076089 http://dx.doi.org/10.1016/j.antiviral.2023.105606 |
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