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Acrylonitrile adducts: design, synthesis and biological evaluation as antimicrobial, haemolytic and thrombolytic agent

In this work, five acrylonitrile adducts were screened for antibacterial activity against Gram-positive Bacillus subtilis, Microbial Type Culture Collection and Gene Bank (MTCC 1305) and Gram-negative Escherichia coli (MTCC 443). Synthesis was followed by aza-Michael addition reaction, where the acr...

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Detalles Bibliográficos
Autores principales: Das, Parineeta, Devi, Nirmala, Gaur, Nisha, Goswami, Swagata, Dutta, Dhiraj, Dubey, Rama, Puzari, Amrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110592/
https://www.ncbi.nlm.nih.gov/pubmed/37069316
http://dx.doi.org/10.1038/s41598-023-33605-1