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Imbalanced expression of cation-chloride cotransporters as a potential therapeutic target in an Angelman syndrome mouse model
Angelman syndrome is a neurodevelopmental disorder caused by loss of function of the maternally expressed UBE3A gene. Treatments for the main manifestations, including cognitive dysfunction or epilepsy, are still under development. Recently, the Cl(−) importer Na(+)-K(+)-Cl(−) cotransporter 1 (NKCC1...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110603/ https://www.ncbi.nlm.nih.gov/pubmed/37069177 http://dx.doi.org/10.1038/s41598-023-32376-z |