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IKKα inhibition re-sensitizes acquired adriamycin-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis

IKKα has been shown to be responsible of multiple pro-tumorigenic functions and therapy resistance independent of canonical NF-κB, but its role in acquired chemotherapy resistance in breast cancer remains unclarified. In this study, we obtained pre-treatment biopsy and post-treatment mastectomy spec...

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Detalles Bibliográficos
Autores principales: Liao, Jian, Qin, Qing-hong, Lv, Fa-you, Huang, Zhen, Lian, Bin, Wei, Chang-yuan, Mo, Qin-guo, Tan, Qi-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110611/
https://www.ncbi.nlm.nih.gov/pubmed/37069240
http://dx.doi.org/10.1038/s41598-023-33358-x