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Central cavity dehydration as a gating mechanism of potassium channels

The hydrophobic gating model, in which ion permeation is inhibited by the hydrophobicity, rather than a physical occlusion of the nanopore, functions in various ion channels including potassium channels. Available research focused on the energy barriers for ion/water conduction due to the hydrophobi...

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Detalles Bibliográficos
Autores principales: Gu, Ruo-Xu, de Groot, Bert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110622/
https://www.ncbi.nlm.nih.gov/pubmed/37069187
http://dx.doi.org/10.1038/s41467-023-37531-8