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Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2

Hexahydro-1,3,5-trinitro-1,3,5-triazine, or Royal Demolition Explosive (RDX), is a major component of plastic explosives such as C-4. Acute exposures from intentional or accidental ingestion are a documented clinical concern, especially among young male U.S. service members in the armed forces. When...

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Detalles Bibliográficos
Autores principales: Mundy, Paige C., Werner, Alicia, Singh, Latika, Singh, Vikrant, Mendieta, Rosalia, Patullo, Caitlyn E., Wulff, Heike, Lein, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110628/
https://www.ncbi.nlm.nih.gov/pubmed/36912926
http://dx.doi.org/10.1007/s00204-023-03475-7