Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells

Although T cells can develop into an exhausted state in the tumour microenvironment, tumour infiltrating T cells (TILs) are important to control tumour growth. By analysing single cell RNA-sequencing data from human tumours, we found that the transcription factors Early Growth Response 2 (EGR2) and...

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Detalles Bibliográficos
Autores principales: Symonds, Alistair L. J., Miao, Tizong, Busharat, Zabreen, Li, Suling, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110685/
https://www.ncbi.nlm.nih.gov/pubmed/36342511
http://dx.doi.org/10.1007/s00262-022-03319-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110685/
https://www.ncbi.nlm.nih.gov/pubmed/36342511
http://dx.doi.org/10.1007/s00262-022-03319-w

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