Somatic ARID1A mutation stratifies patients with gastric cancer to PD-1 blockade and adjuvant chemotherapy

BACKGROUND: AT-rich interaction domain 1A (ARID1A) encodes a vital component of switch/sucrose non-fermentable chromatin-remodeling complex. Given its association with genomic instability, we conducted this study to determine whether ARID1A mutation status had an impact on therapeutic responsiveness...

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Detalles Bibliográficos
Autores principales: Gu, Yun, Zhang, Puran, Wang, Jieti, Lin, Chao, Liu, Hao, Li, He, He, Hongyong, Li, Ruochen, Zhang, Heng, Zhang, Weijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110689/
https://www.ncbi.nlm.nih.gov/pubmed/36369379
http://dx.doi.org/10.1007/s00262-022-03326-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110689/
https://www.ncbi.nlm.nih.gov/pubmed/36369379
http://dx.doi.org/10.1007/s00262-022-03326-x

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