Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell–cell interaction with tumor-associated macrophage

Tumor-associated macrophage (TAM)-derived IL-6 is involved in small-cell lung cancer (SCLC) progression and chemoresistance via the activation of signal transducer and activator of transcription 3 (STAT3) in the tumor microenvironment. This study aimed to identify natural compounds that suppress cel...

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Detalles Bibliográficos
Autores principales: Mito, Remi, Iriki, Toyohisa, Fujiwara, Yukio, Pan, Cheng, Ikeda, Tsuyoshi, Nohara, Toshihiro, Suzuki, Makoto, Sakagami, Takuro, Komohara, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110690/
https://www.ncbi.nlm.nih.gov/pubmed/36961655
http://dx.doi.org/10.1007/s13577-023-00895-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110690/
https://www.ncbi.nlm.nih.gov/pubmed/36961655
http://dx.doi.org/10.1007/s13577-023-00895-6

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