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Expansions of tumor-reactive Vdelta1 gamma-delta T cells in newly diagnosed patients with chronic myeloid leukemia

Recent studies have underscored the importance of gamma-delta (γδ) T cells in mediating potent MHC-unrestricted cytotoxicity in numerous malignancies. Here, we analyzed Vδ1 and Vδ2 γδ T cell subsets in newly diagnosed chronic myeloid leukemia (CML) patients (n = 40) who had initiated tyrosine kinase...

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Detalles Bibliográficos
Autores principales: Knight, Andrea, Piskacek, Martin, Jurajda, Michal, Prochazkova, Jirina, Racil, Zdenek, Zackova, Daniela, Mayer, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110709/
https://www.ncbi.nlm.nih.gov/pubmed/36376516
http://dx.doi.org/10.1007/s00262-022-03312-3