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Local immunotherapy with the RNA-based immune stimulator CV8102 induces substantial anti-tumor responses and enhances checkpoint inhibitor activity

Immunotherapy has revolutionized cancer treatment in recent years. Although currently approved checkpoint inhibitors (CPIs) yield remarkable anti-tumoral responses in several cancer types, a substantial proportion of patients do not benefit from such therapies. Local activation of innate immune sign...

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Detalles Bibliográficos
Autores principales: Lutz, Johannes, Meister, Michael, Habbeddine, Mohamed, Fiedler, Katja, Kowalczyk, Aleksandra, Heidenreich, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110722/
https://www.ncbi.nlm.nih.gov/pubmed/36319717
http://dx.doi.org/10.1007/s00262-022-03311-4