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Local immunotherapy with the RNA-based immune stimulator CV8102 induces substantial anti-tumor responses and enhances checkpoint inhibitor activity
Immunotherapy has revolutionized cancer treatment in recent years. Although currently approved checkpoint inhibitors (CPIs) yield remarkable anti-tumoral responses in several cancer types, a substantial proportion of patients do not benefit from such therapies. Local activation of innate immune sign...
Autores principales: | Lutz, Johannes, Meister, Michael, Habbeddine, Mohamed, Fiedler, Katja, Kowalczyk, Aleksandra, Heidenreich, Regina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110722/ https://www.ncbi.nlm.nih.gov/pubmed/36319717 http://dx.doi.org/10.1007/s00262-022-03311-4 |
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