LZM008, a proposed tocilizumab biosimilar: Pharmacokinetics, safety, and immunogenicity profiles compared with ACTEMRA(®) in Chinese healthy male subjects

Background: This study aimed to investigate the pharmacokinetics, safety, and immunogenicity of recombinant humanized anti-human IL-6R monoclonal antibody injection, LZM008, and evaluate the pharmacokinetic similarity between LZM008 and tocilizumab (ACTEMRA(®)) in Chinese healthy male subjects. Rese...

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Detalles Bibliográficos
Autores principales: Cao, Guoying, Wang, Jingjing, He, Jinjie, Hu, Yingying, Yang, Haijing, Que, Linling, Gu, Xianghong, Yu, Jicheng, Wu, Xiaojie, Wu, Jufang, Fang, Wei, He, Qing, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110837/
https://www.ncbi.nlm.nih.gov/pubmed/37081963
http://dx.doi.org/10.3389/fphar.2023.1111893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110837/
https://www.ncbi.nlm.nih.gov/pubmed/37081963
http://dx.doi.org/10.3389/fphar.2023.1111893

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