Integrating single-cell RNA-seq and spatial transcriptomics reveals MDK-NCL dependent immunosuppressive environment in endometrial carcinoma

OBJECTIVES: The tumor microenvironment (TME) play important roles in progression of endometrial carcinoma (EC). We aimed to assess the cell populations in TME of EC. METHODS: We downloaded datasets of single-cell RNA-seq (scRNA-seq) and spatial transcriptome (ST) for EC from GEO, and downloaded RNA-...

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Detalles Bibliográficos
Autores principales: Yu, Xinnian, Xie, Linjun, Ge, Jianjuan, Li, Huixin, Zhong, Shanliang, Liu, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110842/
https://www.ncbi.nlm.nih.gov/pubmed/37081869
http://dx.doi.org/10.3389/fimmu.2023.1145300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110842/
https://www.ncbi.nlm.nih.gov/pubmed/37081869
http://dx.doi.org/10.3389/fimmu.2023.1145300

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