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Low-dose of caffeine alleviates high altitude pulmonary edema via regulating mitochondrial quality control process in AT1 cells

Backgrounds: High-altitude pulmonary edema (HAPE) is a life-threatening disease without effective drugs. Caffeine is a small molecule compound with antioxidant biological activity used to treat respiratory distress syndrome. However, it is unclear whether caffeine plays a role in alleviating HAPE. M...

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Detalles Bibliográficos
Autores principales: Tian, Liuyang, Jia, Zhilong, Yan, Yan, Jia, Qian, Shi, Wenjie, Cui, Saijia, Chen, Huining, Han, Yang, Zhao, Xiaojing, He, Kunlun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110878/
https://www.ncbi.nlm.nih.gov/pubmed/37081967
http://dx.doi.org/10.3389/fphar.2023.1155414