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Association between treatment failure in patients with early syphilis and penicillin resistance-related gene mutations of Treponema pallidum: Protocol for a multicentre nested case–control study

BACKGROUND: The widespread occurrence of syphilis remains a global public health problem. Although penicillin has been recommended as the first-line therapy for syphilis for more than 70 years, treatment failure occurs in 10–20% of patients with early syphilis. Recent studies have reported varied si...

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Detalles Bibliográficos
Autores principales: Mi, Hong-Fei, Shen, Xu, Chen, Xiao-Qing, Zhang, Xiao-Luo, Ke, Wu-Jian, Xiao, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110954/
https://www.ncbi.nlm.nih.gov/pubmed/37081834
http://dx.doi.org/10.3389/fmed.2023.1131921