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Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing

Molecular subtyping of brain tissue provides insights into the heterogeneity of common neurodegenerative conditions, such as Alzheimer’s disease. However, existing subtyping studies have mostly focused on single data modalities and only those individuals with severe cognitive impairment. To address...

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Detalles Bibliográficos
Autores principales: Yang, Mu, Matan-Lithwick, Stuart, Wang, Yanling, De Jager, Philip L, Bennett, David A, Felsky, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110975/
https://www.ncbi.nlm.nih.gov/pubmed/37082508
http://dx.doi.org/10.1093/braincomms/fcad110