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Circulating neutrophil extracellular trap (NET)-forming ‘rogue’ neutrophil subset, immunotype [DEspR + CD11b +], mediate multi-organ failure in COVID-19—an observational study

BACKGROUND: Cumulative research show association of neutrophils and neutrophil extracellular traps (NETs) with poor outcomes in severe COVID-19. However, to date, there is no curative intent therapy able to block neutrophil/NETs-mediated progression of multi-organ dysfunction. Because of emerging ne...

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Detalles Bibliográficos
Autores principales: Herrera, Victoria L. M., Bosch, Nicholas A., Lok, Judith J., Nguyen, Mai Q., Lenae, Kaitriona A., deKay, Joanne T., Ryzhov, Sergey V., Seder, David B., Ruiz-Opazo, Nelson, Walkey, Allan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111078/
https://www.ncbi.nlm.nih.gov/pubmed/37096233
http://dx.doi.org/10.1186/s41231-023-00143-x