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Disease association and comparative genomics of compositional bias in human proteins

Background: The evolutionary rate of disordered protein regions varies greatly due to the lack of structural constraints. So far, few studies have investigated the presence/absence patterns of compositional bias, indicative of disorder, across phylogenies in conjunction with human disease. In this s...

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Detalles Bibliográficos
Autores principales: Kouros, Christos E., Makri, Vasiliki, Ouzounis, Christos A., Chasapi, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111144/
https://www.ncbi.nlm.nih.gov/pubmed/37082000
http://dx.doi.org/10.12688/f1000research.129929.2