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Atorvastatin and ezetimibe protect against hypercholesterolemia-induced lung oxidative stress, inflammation, and fibrosis in rats

BACKGROUND: Hypercholesterolemia is a major risk factor for interstitial lung disease (ILD). Atorvastatin and ezetimibe are antilipemic drugs that have pleiotropic effects. However, their effects on pulmonary fibrosis prevention and the mechanisms underlying hypercholesterolemia have not been fully...

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Detalles Bibliográficos
Autores principales: Seenak, Porrnthanate, Kumphune, Sarawut, Prasitsak, Thanit, Nernpermpisooth, Nitirut, Malakul, Wachirawadee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111198/
https://www.ncbi.nlm.nih.gov/pubmed/37082028
http://dx.doi.org/10.3389/fmed.2022.1039707