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F-box and WD repeat domain containing 7 inhibits the activation of hepatic stellate cells by degrading delta-like ligand 1 to block Notch signaling pathway

Hepatic fibrosis (HF) is a precursor of liver cirrhosis, and activated hepatic stellate cells are an important driver of fibrosis. F-box and WD repeat domain containing 7 (FBXW7) expression level is down-regulated in HF, but the underlying mechanism is yet to be elucidated. The interaction between F...

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Detalles Bibliográficos
Autores principales: Sun, Yufeng, He, Lili, Guo, Peiran, Li, Fenghua, Wang, Bo, Zhang, Yifan, An, Kai, Peng, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111210/
https://www.ncbi.nlm.nih.gov/pubmed/37082613
http://dx.doi.org/10.1515/med-2023-0634