NADPH oxidase 2 limits amplification of IL-1β–G-CSF axis and an immature neutrophil subset in murine lung inflammation

The leukocyte NADPH oxidase 2 (NOX2) regulates inflammation independent of its antimicrobial activity. Inherited defects in NOX2 lead to chronic granulomatous disease (CGD), associated with recurrent bacterial and fungal infections, often with excessive neutrophilic inflammation that results in sign...

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Detalles Bibliográficos
Autores principales: Song, Zhimin, Bhattacharya, Sourav, Huang, Guangming, Greenberg, Zev J., Yang, Wei, Bagaitkar, Juhi, Schuettpelz, Laura G., Dinauer, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111367/
https://www.ncbi.nlm.nih.gov/pubmed/36103336
http://dx.doi.org/10.1182/bloodadvances.2022007652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111367/
https://www.ncbi.nlm.nih.gov/pubmed/36103336
http://dx.doi.org/10.1182/bloodadvances.2022007652

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