Optimization of Host Cell-Compatible, Antimicrobial Peptides Effective against Biofilms and Clinical Isolates of Drug-Resistant Bacteria

[Image: see text] Here, we describe the continued synthetic molecular evolution of a lineage of host-compatible antimicrobial peptides (AMP) intended for the treatment of wounds infected with drug-resistant, biofilm-forming bacteria. The peptides tested are variants of an evolved AMP called d-amino...

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Detalles Bibliográficos
Autores principales: Ghimire, Jenisha, Hart, Robert J., Soldano, Anabel, Chen, Charles H., Guha, Shantanu, Hoffmann, Joseph P., Hall, Kalen M., Sun, Leisheng, Nelson, Benjamin J., Lu, Timothy K., Kolls, Jay K., Rivera, Mario, Morici, Lisa A., Wimley, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111420/
https://www.ncbi.nlm.nih.gov/pubmed/36961222
http://dx.doi.org/10.1021/acsinfecdis.2c00640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111420/
https://www.ncbi.nlm.nih.gov/pubmed/36961222
http://dx.doi.org/10.1021/acsinfecdis.2c00640

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