Cargando…

Antagonizing FcαR1 (CD89) as treatment in IgA-mediated chronic inflammation and autoimmunity

INTRODUCTION: Immunoglobulin A (IgA) is mostly considered as a non-inflammatory regulator at mucosal areas. However, previous work of our group showed that IgA can also be involved in disease pathology, because it provides a potent stimulus to activate neutrophils after crosslinking of surface CD89...

Descripción completa

Detalles Bibliográficos
Autores principales: van Delft, Myrthe A. M., Aleyd, Esil, van der Mast, Richard, de Jong, Niels, Boon, Louis, Simons, Peter J., van Egmond, Marjolein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111428/
https://www.ncbi.nlm.nih.gov/pubmed/37081893
http://dx.doi.org/10.3389/fimmu.2023.1118539