Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model

BACKGROUND: Deep vein thrombosis (DVT) is the primary cause of pulmonary embolism and the third most life‐threatening cardiovascular disease in North America. Post‐DVT anticoagulants, such as warfarin, heparin, and direct oral anticoagulants, reduce the incidence of subsequent venous thrombi. Howeve...

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Detalles Bibliográficos
Autores principales: Lapointe, Catherine, Vincent, Laurence, Giguère, Hugo, Auger‐Messier, Mannix, Schwertani, Adel, Jin, Denan, Takai, Shinji, Pejler, Gunnar, Sirois, Martin G., Tinel, Hanna, Heitmeier, Stefan, D'Orléans‐Juste, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111474/
https://www.ncbi.nlm.nih.gov/pubmed/36752268
http://dx.doi.org/10.1161/JAHA.122.028056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111474/
https://www.ncbi.nlm.nih.gov/pubmed/36752268
http://dx.doi.org/10.1161/JAHA.122.028056

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