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Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model
BACKGROUND: Deep vein thrombosis (DVT) is the primary cause of pulmonary embolism and the third most life‐threatening cardiovascular disease in North America. Post‐DVT anticoagulants, such as warfarin, heparin, and direct oral anticoagulants, reduce the incidence of subsequent venous thrombi. Howeve...
Autores principales: | Lapointe, Catherine, Vincent, Laurence, Giguère, Hugo, Auger‐Messier, Mannix, Schwertani, Adel, Jin, Denan, Takai, Shinji, Pejler, Gunnar, Sirois, Martin G., Tinel, Hanna, Heitmeier, Stefan, D'Orléans‐Juste, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111474/ https://www.ncbi.nlm.nih.gov/pubmed/36752268 http://dx.doi.org/10.1161/JAHA.122.028056 |
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